HOMEPRODUCTSCOMPANYCONTACTFAQResearchDictionaryPharmaSign Up FREE or Login

High complication rate of bile duct stents in patients with chronic alcoholic pancreatitis due to noncompliance.

AbstractBACKGROUND AND STUDY AIMS:
Biliary obstruction in chronic pancreatitis is frequently treated by endoscopic insertion of a plastic stent into the common bile duct, a therapy regarded as having a low complication rate. The aim of this study is to analyze the frequency and severity of complications caused by biliary stents in patients with chronic alcoholic pancreatitis.
PATIENTS AND METHODS:
We retrospectively analyzed all our patients with chronic pancreatitis (n = 14) who were provided with a plastic stent for biliary stenosis between June 1993 and December 1997. Stent exchanges were followed until December 1998.
RESULTS:
Stent insertion was performed without early complications and was successful in each patient. Only two patients were admitted after 3-4 months at the scheduled dates for stent exchange, both without complications. In one of these patients, the bile duct stenosis was reopened after two stent exchanges over a total period of 8 months. Most of our patients (n=12) did not come at the arranged dates for stent exchange. They were repeatedly admitted (mean 2.9 times/patient, range 1-5) as emergency cases with severe complications of biliary obstruction, such as cholangitis or biliary sepsis. Reopening of the bile duct stenosis was not achieved in these patients.
CONCLUSIONS:
We associate the high rate of complications with the noncompliance of our patients, who were all alcoholics. The high incidence of late complications in noncompliant patients is a limitation of biliary stenting, and appears to be potentially harmful.
AuthorsK Kiehne, U R Fölsch, R Nitsche
JournalEndoscopy (Endoscopy) Vol. 32 Issue 5 Pg. 377-80 (May 2000) ISSN: 0013-726X [Print] Germany
PMID10817175 (Publication Type: Comparative Study, Journal Article)
Topics
  • Adult
  • Aged
  • Aged, 80 and over
  • Cholangiopancreatography, Endoscopic Retrograde
  • Cholestasis, Extrahepatic (diagnosis, etiology, surgery)
  • Common Bile Duct (diagnostic imaging, surgery)
  • Female
  • Humans
  • Male
  • Middle Aged
  • Pancreatitis, Alcoholic (complications)
  • Patient Compliance
  • Postoperative Complications (diagnosis, surgery)
  • Reoperation
  • Retrospective Studies
  • Stents (adverse effects)
  • Treatment Outcome
  • Ultrasonography

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.
Realize the full power of the drug-disease research graph!


Choose Username:
Email:
Password:
Verify Password:
Enter Code Shown: