Concurrent chemoimmunotherapy in metastatic clear cell sarcoma: a case report.

Clear cell sarcoma is a rare tumor with a poor prognosis. The therapeutic approach in the metastatic disease stage is controversial: to the authors' knowledge the use of concurrent chemoimmunotherapy has not been previously reported. We present a case of a 57-year-old male with metastatic clear cell sarcoma treated simultaneously with subcutaneous interferon-a 2b and six courses of chemotherapy according to the CyVEDIC regimen. Disease stabilization lasting 17 months was achieved.
AuthorsS Lauro, F Bordin, L Trasatti, G Lanzetta, C Della Rocca, L Frati
JournalTumori (Tumori) 1999 Nov-Dec Vol. 85 Issue 6 Pg. 512-4 ISSN: 0300-8916 [Print] ITALY
PMID10774576 (Publication Type: Case Reports, Journal Article)
Chemical References
  • Interferon-alpha
  • Recombinant Proteins
  • Epirubicin
  • Vincristine
  • Dacarbazine
  • Cyclophosphamide
  • interferon alfa-2b
  • Antineoplastic Combined Chemotherapy Protocols (therapeutic use)
  • Cyclophosphamide (administration & dosage)
  • Dacarbazine (administration & dosage)
  • Disease Progression
  • Epirubicin (administration & dosage)
  • Fatal Outcome
  • Humans
  • Immunotherapy (methods)
  • Interferon-alpha (therapeutic use)
  • Leg
  • Lung Neoplasms (complications, drug therapy, secondary, therapy)
  • Male
  • Middle Aged
  • Pleural Effusion, Malignant (etiology)
  • Recombinant Proteins
  • Sarcoma, Clear Cell (drug therapy, pathology, therapy)
  • Treatment Outcome
  • Vincristine (administration & dosage)

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