Abstract | OBJECTIVE: DESIGN: Prospective case series, observational study. SETTING: A university hospital neonatal intensive care unit. PATIENTS: INTERVENTIONS: Mechanical or bag mask ventilation and antagonization with naloxone. MEASUREMENTS AND MAIN RESULTS: CONCLUSION: Even low doses of fentanyl can lead to thoracic rigidity in neonates. Additionally, we observed laryngospasm in two patients and speculate that it might be a variant of muscle rigidity.
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Authors | H Fahnenstich, J Steffan, N Kau, P Bartmann |
Journal | Critical care medicine
(Crit Care Med)
Vol. 28
Issue 3
Pg. 836-9
(Mar 2000)
ISSN: 0090-3493 [Print] United States |
PMID | 10752838
(Publication Type: Journal Article)
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Chemical References |
- Narcotic Antagonists
- Narcotics
- Naloxone
- Fentanyl
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Topics |
- Fentanyl
(adverse effects)
- Humans
- Hypercapnia
(etiology)
- Hypoxia
(etiology)
- Infant, Newborn
- Infant, Premature
- Laryngismus
(chemically induced, drug therapy)
- Naloxone
(therapeutic use)
- Narcotic Antagonists
(therapeutic use)
- Narcotics
(adverse effects)
- Prospective Studies
- Respiratory Distress Syndrome, Newborn
(etiology)
- Thoracic Diseases
(chemically induced, complications, drug therapy)
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