Abstract | PURPOSE: MATERIALS AND METHODS: Twenty-nine patients (17 women, 12 men; age range, 39-91 years) referred with a diagnosis of rectal carcinoma were examined. Analysis of the rectal wall and staging of the tumor were performed. In all patients, the MR imaging findings were correlated with the histopathologic findings. RESULTS: The contrast material enema caused distention of the rectum and an intraluminal signal void, whereas the gadodiamide injection caused enhancement of the mucosa on T1-weighted images. This enhancement enabled evaluation of the normal rectal wall and differentiation of the mucosa, tunica muscularis, and perirectal space, which was not possible on the nonenhanced images. Double-contrast ( ferristene solution plus gadodiamide) MR imaging was superior to imaging with only ferristene-based contrast material and had a sensitivity of 100%, specificity of 70%, and accuracy of 90% in distinguishing tumor stages worse than Dukes A. CONCLUSION: Double contrast material-enhanced MR imaging enables accurate rectal carcinoma staging, which is not possible at nonenhanced imaging.
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Authors | N O Wallengren, S Holtås, A Andrén-Sandberg, E Jonsson, D T Kristoffersson, S McGill |
Journal | Radiology
(Radiology)
Vol. 215
Issue 1
Pg. 108-14
(Apr 2000)
ISSN: 0033-8419 [Print] United States |
PMID | 10751475
(Publication Type: Journal Article)
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Chemical References |
- Contrast Media
- Ferric Compounds
- ferristene
- gadodiamide
- Gadolinium DTPA
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Topics |
- Adult
- Aged
- Aged, 80 and over
- Artifacts
- Carcinoma
(diagnosis, pathology)
- Confidence Intervals
- Contrast Media
(administration & dosage)
- Enema
- Evaluation Studies as Topic
- Female
- Ferric Compounds
(administration & dosage)
- Gadolinium DTPA
(administration & dosage)
- Humans
- Image Enhancement
(methods)
- Injections, Intravenous
- Intestinal Mucosa
(pathology)
- Lymph Nodes
(pathology)
- Magnetic Resonance Imaging
(methods)
- Male
- Middle Aged
- Muscle, Smooth
(pathology)
- Preoperative Care
- ROC Curve
- Rectal Neoplasms
(diagnosis, pathology)
- Rectum
(pathology)
- Sensitivity and Specificity
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