Clinical results of Ahmed glaucoma valve implantation in refractory glaucoma with adjunctive mitomycin C.

Abstract

OBJECTIVE:

To study the surgical outcome and complications of Ahmed glaucoma valve (AGV) implantation with mitomycin C (MMC) in refractory glaucoma.

PATIENTS AND METHODS:

The authors retrospectively reviewed the records of 40 eyes in 37 consecutive patients who underwent combined AGV with MMC (0.4 mg/mL; 5 minutes). All patients had a minimum of 6 months of follow-up. Outcome measures were best corrected visual acuity, intraocular pressure (IOP), the number of medications, success rates, and the incidence of complications.

RESULTS:

The Kaplan-Meier life table analysis revealed that the probabilities of surgical success based on our success criteria at 1 year and 2 years postoperatively were 80% and 77%, respectively. Postoperative IOP was significantly lower at all follow-up intervals. At the final visit fewer glaucoma medications were used (2.5 vs 0.7, preoperative vs postoperative). The most frequent complication was hypotony (17%).

CONCLUSION:

In this retrospective case series with relatively short follow-ups, AGV implantation with mitomycin C in refractory glaucoma appears to be effective without increased complication rates.

• Authors: M S Kook, J Yoon, J Kim, M S Lee
• Journal: Ophthalmic surgery and lasers (Ophthalmic Surg Lasers) 2000 Mar-Apr Vol. 31 Issue 2 Pg. 100-6 ISSN: 1082-3069 [Print] United States
• PMID: 10743919 (Publication Type: Journal Article)

Chemical References

• Mitomycin

Topics

• Adolescent
• Adult
• Aged
• Aged, 80 and over
• Chemotherapy, Adjuvant
• Child
• Child, Preschool
• Female
• Glaucoma (drug therapy, surgery)
• Glaucoma Drainage Implants
• Humans
• Intraocular Pressure
• Male
• Middle Aged
• Mitomycin (therapeutic use)
• Postoperative Complications
• Prosthesis Implantation
• Retrospective Studies
• Treatment Outcome
• Visual Acuity