Abstract | PURPOSE: To evaluate the effect of irrigation solution and temperature on pupil diameter, corneal endothelium, and corneal pachymetry during and after phacoemulsification. SETTING: Klinik Dardenne, Bonn, Germany. METHODS: Eighty patients who had cataract surgery by phacoemulsification were assigned to 1 of 4 cross-classified groups and had intraoperative irrigation with room-temperature or refrigerated fortified balanced salt solution ( BSS Plus) or modified Ringer's solution. Pupil diameters were recorded at different stages during the surgery. Epithelial cell counts and pachymetry were determined before and 1 day after surgery. RESULTS: The solution temperature did not affect any parameter. The type of solution did not influence endothelial cell loss; however, the solution had a significant effect on corneal pachymetry 1 day postoperatively. The corneas irrigated with BSS Plus were less swollen than the corneas irrigated with Ringer's solution. By day 14, corneal thickness was equal among all groups. CONCLUSION: Long-term results were equally favorable in all 4 groups. However BSS Plus induced less short-term corneal swelling than Ringer's solution. From these findings, it appears that BSS Plus may decrease corneal risk in cases with compromised corneas or prolonged surgery.
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Authors | A M Joussen, U Barth, H Cubuk, H Koch |
Journal | Journal of cataract and refractive surgery
(J Cataract Refract Surg)
Vol. 26
Issue 3
Pg. 392-7
(Mar 2000)
ISSN: 0886-3350 [Print] United States |
PMID | 10713235
(Publication Type: Clinical Trial, Comparative Study, Controlled Clinical Trial, Journal Article)
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Chemical References |
- Bicarbonates
- Drug Combinations
- Isotonic Solutions
- Ophthalmic Solutions
- glutathione-bicarbonate-Ringer solution
- Ringer's Solution
- Glutathione
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Topics |
- Adult
- Aged
- Aged, 80 and over
- Bicarbonates
(administration & dosage)
- Cell Count
- Cold Temperature
- Corneal Diseases
(prevention & control)
- Corneal Stroma
(cytology, drug effects)
- Drug Combinations
- Endothelium, Corneal
(cytology, drug effects)
- Female
- Glutathione
(administration & dosage)
- Humans
- Intraoperative Period
- Isotonic Solutions
(administration & dosage)
- Lens Implantation, Intraocular
- Male
- Middle Aged
- Ophthalmic Solutions
- Phacoemulsification
- Postoperative Complications
(prevention & control)
- Pupil
(drug effects)
- Ringer's Solution
- Safety
- Therapeutic Irrigation
- Treatment Outcome
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