Abstract | PURPOSE: METHODS: RESULTS: There were 20 oculomotor, 33 trochlear, 37 abducens, and 10 facial nerve palsy cases. The median duration of diabetes was 6 years for cases and 7 years for control subjects. There were 34 cases (34%) who had used aspirin for a mean duration of 5.5 years before the onset of the cranial nerve palsy and 49 control subjects (30.1%) who had used aspirin for a mean duration of 4.3 years. There were no significant differences between cases and control subjects for duration of diabetes (P =.94); aspirin use (P =.51), duration (P =.50), and dosage (P =.89); tobacco use (P =.73) and consumption (P =.45); and proportion of cardiac disease (P =.17). Cerebrovascular disease was significantly less common among palsy cases than nonpalsy control subjects (P<.001). There was no significant difference in the odds of a patient having cranial nerve palsy in the aspirin group compared with the nonaspirin group (odds ratio, 1.12; 95% confidence interval, 0.70-2.04). CONCLUSION:
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Authors | L N Johnson, S W Stetson, G B Krohel, C L Cipollo, R W Madsen |
Journal | American journal of ophthalmology
(Am J Ophthalmol)
Vol. 129
Issue 3
Pg. 367-71
(Mar 2000)
ISSN: 0002-9394 [Print] United States |
PMID | 10704554
(Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
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Chemical References |
- Cyclooxygenase Inhibitors
- Platelet Aggregation Inhibitors
- Aspirin
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Topics |
- Acute Disease
- Aged
- Aged, 80 and over
- Aspirin
(therapeutic use)
- Case-Control Studies
- Cranial Nerve Diseases
(etiology, prevention & control)
- Cranial Nerves
(blood supply, pathology)
- Cyclooxygenase Inhibitors
(therapeutic use)
- Diabetes Complications
- Diplopia
(etiology, physiopathology)
- Facial Paralysis
(etiology, physiopathology)
- Female
- Humans
- Hypertension
(complications)
- Ischemia
(etiology, prevention & control)
- Male
- Middle Aged
- Platelet Aggregation Inhibitors
(therapeutic use)
- Retrospective Studies
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