[A case of advanced gastric cancer with hepatic metastasis successfully treated by combined chemotherapy with UFT and lentinan].

Abstract

We have experienced successful treatment of a hepatic metastasis of gastric cancer with UFT and lentinan. The patient was a 65-year-old male, who underwent distal gastrectomy for gastric cancer with hepatic and lymphatic metastases. After operation, administrations of UFT 300 mg/day and lentinan 2 mg/2 weeks were given, and the hepatic metastasis disappeared by 17 months. We performed a resection of the residual stomach and lymphatic metastasis at 52 months after operation. For over 5 years the patient has shown no evidence of a recurrence of the hepatic metastasis. This chemotherapy regimen was very effective and improved the patients quality of life.

• Authors: T Yamada, A Watanabe, S Sadou, T Nishinuma, H Tsurui, T Watanabe, H Nakano
• Journal: Gan to kagaku ryoho. Cancer & chemotherapy (Gan To Kagaku Ryoho) Vol. 27 Issue 2 Pg. 281-4 (Feb 2000) ISSN: 0385-0684 [Print] Japan
• PMID: 10700901 (Publication Type: Case Reports, English Abstract, Journal Article)

Chemical References

• Tegafur
• Lentinan
• Uracil

Topics

• Adenocarcinoma (drug therapy, secondary, surgery)
• Aged
• Antineoplastic Combined Chemotherapy Protocols (therapeutic use)
• Drug Administration Schedule
• Gastrectomy
• Humans
• Lentinan (administration & dosage)
• Liver Neoplasms (drug therapy, secondary)
• Lymphatic Metastasis
• Male
• Stomach Neoplasms (drug therapy, pathology, surgery)
• Tegafur (administration & dosage)
• Uracil (administration & dosage)