Abstract |
Forty-five lung cancer patients who had recurrence and/or endobronchial obstruction were treated with intrabronchial radiotherapy (IBRT). The majority had been heavily treated previously, mainly by external radiotherapy; six patients were treated surgically. IBRT was given with high-dose-rate equipment, either 18 Gy in three fractions or 15 Gy as a single dose was originally planned. For different reasons several patients received other regimens. Palliation of dyspnoea was obtained in 64% of the patients. Palliation of hemoptysis (12/14) and cough (11/17) was registered, as well as improvement in atelectasis in 11/26 patients. Palliation of dyspnoea was enhanced with an IBRT dose > 15 Gy. The median survival after IBRT was 13 weeks. Fatal hemoptysis (FH) occurred in 12 patients; 10 of these within 6 months after treatment. The risk of FH significantly increased with an IBRT dose > 15 Gy.
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Authors | R Hatlevoll, K O Karlsen, E Skovlund |
Journal | Acta oncologica (Stockholm, Sweden)
(Acta Oncol)
Vol. 38
Issue 8
Pg. 999-1004
( 1999)
ISSN: 0284-186X [Print] England |
PMID | 10665752
(Publication Type: Journal Article)
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Topics |
- Bronchial Neoplasms
(complications, radiotherapy, secondary)
- Dyspnea
(etiology)
- Female
- Hemoptysis
(etiology)
- Humans
- Lung Neoplasms
(mortality, pathology)
- Male
- Palliative Care
- Radiotherapy Dosage
- Recurrence
- Retrospective Studies
- Survival Rate
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