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Endobronchial radiotherapy for malignant bronchial obstruction or recurrence.

Abstract
Forty-five lung cancer patients who had recurrence and/or endobronchial obstruction were treated with intrabronchial radiotherapy (IBRT). The majority had been heavily treated previously, mainly by external radiotherapy; six patients were treated surgically. IBRT was given with high-dose-rate equipment, either 18 Gy in three fractions or 15 Gy as a single dose was originally planned. For different reasons several patients received other regimens. Palliation of dyspnoea was obtained in 64% of the patients. Palliation of hemoptysis (12/14) and cough (11/17) was registered, as well as improvement in atelectasis in 11/26 patients. Palliation of dyspnoea was enhanced with an IBRT dose > 15 Gy. The median survival after IBRT was 13 weeks. Fatal hemoptysis (FH) occurred in 12 patients; 10 of these within 6 months after treatment. The risk of FH significantly increased with an IBRT dose > 15 Gy.
AuthorsR Hatlevoll, K O Karlsen, E Skovlund
JournalActa oncologica (Stockholm, Sweden) (Acta Oncol) Vol. 38 Issue 8 Pg. 999-1004 ( 1999) ISSN: 0284-186X [Print] England
PMID10665752 (Publication Type: Journal Article)
Topics
  • Bronchial Neoplasms (complications, radiotherapy, secondary)
  • Dyspnea (etiology)
  • Female
  • Hemoptysis (etiology)
  • Humans
  • Lung Neoplasms (mortality, pathology)
  • Male
  • Palliative Care
  • Radiotherapy Dosage
  • Recurrence
  • Retrospective Studies
  • Survival Rate

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