Abstract | OBJECTIVE: METHODS: The morphologic and immunohistochemical findings were correlated to patient menstrual status, which was categorized as childbearing age (n = 15), perimenopausal (n = 8), and postmenopausal (n = 10). RESULTS:
Fibromatoses in women of childbearing age were more cellular, more mitotically active, and displayed a larger proportion of cells with mild atypia than those in perimenopausal and postmenopausal women. The hormonal status of these 3 groups does not explain the morphologic variations observed in these groups, inasmuch as no immunostaining for any of the hormone receptors was detected in the tumors. CONCLUSIONS:
|
Authors | M Devouassoux-Shisheboran, M D Schammel, Y G Man, F A Tavassoli |
Journal | Archives of pathology & laboratory medicine
(Arch Pathol Lab Med)
Vol. 124
Issue 2
Pg. 276-80
(Feb 2000)
ISSN: 0003-9985 [Print] United States |
PMID | 10656738
(Publication Type: Journal Article)
|
Chemical References |
- Ki-67 Antigen
- Proteins
- Receptors, Androgen
- Receptors, Estrogen
- Receptors, Progesterone
- TFF1 protein, human
- Trefoil Factor-1
- Tumor Suppressor Proteins
|
Topics |
- Adolescent
- Adult
- Age Factors
- Aged
- Aged, 80 and over
- Breast Neoplasms
(chemistry, pathology)
- Female
- Fibroma
(chemistry, pathology)
- Humans
- Immunohistochemistry
- Ki-67 Antigen
(analysis)
- Middle Aged
- Postmenopause
- Premenopause
- Proteins
(analysis)
- Receptors, Androgen
(analysis)
- Receptors, Estrogen
(analysis)
- Receptors, Progesterone
(analysis)
- Trefoil Factor-1
- Tumor Suppressor Proteins
|