Abstract | OBJECTIVES: METHODS: RESULTS:
Prostaglandin E2 production and cyclooxygenase activity were significantly higher in cultures of chondrocytes from osteoarthritic than from healthy joints. Adding IL-1 beta to the osteoarthritic chondrocyte cultures further increased the high cyclooxygenase activity, whereas adding TNF alpha alone had no effect. CONCLUSION:
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Authors | C Jacques, A Sautet, M Moldovan, B Thomas, L Humbert, F Berenbaum |
Journal | Revue du rhumatisme (English ed.)
(Rev Rhum Engl Ed)
Vol. 66
Issue 12
Pg. 701-4
(Dec 1999)
ISSN: 1169-8446 [Print] France |
PMID | 10649604
(Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
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Chemical References |
- Prostaglandin-Endoperoxide Synthases
|
Topics |
- Cartilage
(enzymology)
- Chondrocytes
(enzymology)
- Humans
- Osteoarthritis
(enzymology)
- Prostaglandin-Endoperoxide Synthases
(metabolism)
|