[Cushing's syndrome secondary to bronchial carcinoid tumor: contribution of gammagraphy with 111In-DTPA octreotide in the localization diagnosis].

Abstract

Bronchial carcinoid (BC) is a rare etiology of Cushing syndrome, and difficulties in differential diagnosis with Cushing's disease are often present. We report two cases in which octreotide scintigraphy was an important diagnostic tool. The first patient showed a 1 cm non-specific pulmonary nodule on CT scan that was positive on scintigraphy, being confirmed by surgery. The second case was a man that had been operated but not cured of an ACTH secreting BC that continued with high ACTH levels and negative localization imaging studies. A subsequent scintigraphy showed a positive image suggestive of recurrence. Octreotide scintigraphy may be considered in patients with suspicion of ectopic ACTH syndrome although a positive image in CT scan be present.

• Authors: E Peña González, J L Lampreave Márquez, P León Atance, B Moreno Esteban, A Bittini Copano, E Folqué Gómez
• Journal: Anales de medicina interna (Madrid, Spain : 1984) (An Med Interna) Vol. 16 Issue 11 Pg. 577-9 (Nov 1999) ISSN: 0212-7199 [Print] Spain
• Vernacular Title: Síndrome de Cushing secundario a tumor carcinoide bronquial: valor de la gammagrafía con 111In-DTPA octreotide en el diagnóstico de localización.
• PMID: 10637999 (Publication Type: Case Reports, Journal Article)

Chemical References

• Radiopharmaceuticals
• SDZ 215-811
• Pentetic Acid
• Octreotide

Topics

• Aged
• Bronchial Neoplasms (complications, diagnostic imaging)
• Carcinoid Tumor (complications, diagnostic imaging)
• Cushing Syndrome (etiology)
• Female
• Humans
• Male
• Middle Aged
• Octreotide (analogs & derivatives)
• Pentetic Acid (analogs & derivatives)
• Radionuclide Imaging
• Radiopharmaceuticals