Beneficial effect of piracetam monotherapy on post-ischaemic palatal myoclonus.

Abstract

A 70-year-old hypertensive woman suffered a subarachnoid haemorrhage followed by delayed vasospasm in the basal cerebral arteries. This resulted in multiple ischaemic lesions in the right middle cerebral artery region and contralateral post-ischaemic palatal myoclonus. In this setting, piracetam administered in high doses (24-36 g/day), abolished the myoclonus observed in this patient. Although there is evidence from case reports and clinical trials of the therapeutic efficacy of piracetam in patients with skeletal myoclonus of various causes, to our knowledge this is the first report indicating the beneficial effect of piracetam monotherapy on post-ischaemic palatal myoclonus.

• Authors: D Karacostas, T Doskas, N Artemis, K Vadicolias, I Milonas
• Journal: The Journal of international medical research (J Int Med Res) 1999 Jul-Aug Vol. 27 Issue 4 Pg. 201-5 ISSN: 0300-0605 [Print] England
• PMID: 10599034 (Publication Type: Case Reports, Journal Article)

Chemical References

• Piracetam

Topics

• Aged
• Brain Ischemia (complications)
• Female
• Humans
• Magnetic Resonance Imaging
• Myoclonus (drug therapy, etiology)
• Piracetam (therapeutic use)
• Subarachnoid Hemorrhage (complications)
• Tomography, X-Ray Computed