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Two asymptomatic cases with sarcoidosis demonstrated sequential evolution from radiographic stage I to III within five years.

AbstractThere are no guidelines regarding the treatment of pulmonary sarcoidosis. Generally, oral corticosteroids are considered the first-line treatment for symptomatic patients with pulmonary sarcoidosis. We report here two Japanese cases with pulmonary sarcoidosis who demonstrated sequential evolution from radiographic stage I to III within five years. Although these two cases had no symptoms, persistent, progressive pulmonary involvements were observed on chest X-ray. Considering the effectiveness of corticosteroids on patients with radiographic type II or III sarcoidosis reported by the British Thoracic Society, corticosteroid therapy might be a choice even in asymptomatic cases, if they demonstrate developing pulmonary involvement.
AuthorsS Ishioka, A Maeda, K Hiyama, Y Jougasaki, M Yamakido (Affiliation: Second Department of Internal Medicine, Hiroshima University School of Medicine, Japan.)
JournalHiroshima journal of medical sciences (Hiroshima J Med Sci) Vol. 48 Issue 3 Pg. 101-3 (Sep 1999) ISSN: 0018-2052 JAPAN
PMID10598414 (Publication Type: Case Reports, Journal Article)
Chemical References
  • Adrenal Cortex Hormones
Topics
  • Adrenal Cortex Hormones (therapeutic use)
  • Adult
  • Female
  • Humans
  • Lung Diseases (drug therapy, etiology, radiography)
  • Male
  • Prognosis
  • Sarcoidosis (drug therapy, etiology, radiography)
  • Time Factors