Abstract |
Lymphomatoid granulomatosis (LG) is an uncommon but potentially fatal disease. The disease primarily involves the lungs; however, skin, renal, and central nervous system (CNS) are seen in varying proportions. Neurological involvement occurs in one third of the patients, and confers a worse prognosis. The use of radiotherapy to treat CNS involvement in LG has not been well studied. We report a case of a 33-year-old man with multiple CNS lesions treated successfully with radiotherapy and review 6 other cases in the literature using similar treatment. These cases support the use of radiotherapy for CNS involvement in LG.
|
Authors | T M Petrella, I R Walker, G W Jones, B Leber |
Journal | American journal of hematology
(Am J Hematol)
Vol. 62
Issue 4
Pg. 239-41
(Dec 1999)
ISSN: 0361-8609 [Print] United States |
PMID | 10589080
(Publication Type: Case Reports, Journal Article, Review)
|
Copyright | Copyright 1999 Wiley-Liss, Inc. |
Chemical References |
- Vincristine
- Doxorubicin
- Cyclophosphamide
- Prednisone
|
Topics |
- Adult
- Antineoplastic Combined Chemotherapy Protocols
(therapeutic use)
- Brain Neoplasms
(diagnosis, radiotherapy)
- Cyclophosphamide
(administration & dosage)
- Doxorubicin
(administration & dosage)
- Humans
- Lung Neoplasms
(diagnosis, therapy)
- Lymphomatoid Granulomatosis
(diagnosis, radiotherapy, therapy)
- Magnetic Resonance Imaging
- Male
- Prednisone
(administration & dosage)
- Remission Induction
- Vincristine
(administration & dosage)
|