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Subcorneal pustular dermatosis and IgA lambda myeloma: a uncommon association but probably not coincidental.

AbstractThe present report deals with a case of subcorneal pustular dermatosis (SCPD) associated with IgAlambda myeloma and reviews the literature for similar cases. Three relevant points arise from this case: the association of the dermatosis with an IgAlambda myeloma that, as far as we know, has been described only three times previously; the longest period of time between the onset of the dermatosis and that of the myelopathy observed up to now; the good therapeutic response to etretinate, useful in the management of severe recalcitrant forms of SCPD.
AuthorsM Vaccaro, S P Cannavò, B Guarneri (Affiliation: University of Messina, Institute of Dermatology Policlinico Universitario, via Consolare Valeria Gazzi, 98125 Messina, Italy. Mario.Vaccaro at unime.it)
JournalEuropean journal of dermatology : EJD (Eur J Dermatol) Vol. 9 Issue 8 Pg. 644-6 (Dec 1999) ISSN: 1167-1122 FRANCE
PMID10586134 (Publication Type: Case Reports, Journal Article)
Chemical References
  • Immunoglobulin A
  • Immunoglobulin lambda-Chains
  • Etretinate
Topics
  • Aged
  • Etretinate (therapeutic use)
  • Humans
  • Immunoglobulin A (analysis)
  • Immunoglobulin lambda-Chains
  • Male
  • Multiple Myeloma (complications, immunology)
  • Skin Diseases, Vesiculobullous (complications, drug therapy, pathology)