Abstract | INTRODUCTION: CASE REPORT: A 23-year-old female presented to the emergency department approximately 1-1.5 hours following ingestion of a gulp of triethylene glycol (99%) brake fluid with coma (GCS-3) and metabolic acidemia (pH 7.03, PCO2 44 mm Hg, Bicarbonate 11 mmol/L, anion gap 30 mmol/L, serum creatinine 90 mumol/L). She was intubated and given 100 mmol of intravenous sodium bicarbonate. An ethanol loading dose was administered followed by an infusion to maintain serum ethanol at 100 mg/dL. Acidemia gradually resolved over the next 8 hours and she was extubated 12 hours later. The ethanol infusion was continued for a total of 22 hours. There was no recurrence of acidemia. Serum ethanol, ethylene glycol, and methanol levels were nondetectable on presentation, as was serum salicylate. Urine drug of abuse screen and thin-layer chromatography revealed no other coingested substances. The patient was discharged to a psychiatric ward 36 hours postingestion. CONCLUSION:
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Authors | J Vassiliadis, A Graudins, R P Dowsett |
Journal | Journal of toxicology. Clinical toxicology
(J Toxicol Clin Toxicol)
Vol. 37
Issue 6
Pg. 773-6
( 1999)
ISSN: 0731-3810 [Print] United States |
PMID | 10584590
(Publication Type: Case Reports, Journal Article)
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Chemical References |
- Antidotes
- Ethanol
- triethylene glycol
- Polyethylene Glycols
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Topics |
- Acidosis
(blood, chemically induced, drug therapy)
- Adult
- Antidotes
(therapeutic use)
- Coma
(chemically induced, drug therapy)
- Ethanol
(administration & dosage, therapeutic use)
- Female
- Humans
- Infusions, Intravenous
- Polyethylene Glycols
(chemistry, poisoning)
- Suicide, Attempted
- Treatment Outcome
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