[Experience with glyciphonic ointment for malignant and precancerous lesions of the skin].

Abstract

Skin was smeared with glyciphonic ointment containing 30% of methylphosphonic diglycidyl ether (Tatkhimfarmpreparaty Company) in 495 patients with histologically confirmed basalioma and 36 patients with senile keratosis. During daily application necrotic tissue was removed. Considerable decomposition of tumor occurred on day 6 or later. It took the wound 9-12, seldom, 15 days to heal, with scars forming on days 15-20. Stable cure was registered (5-7 yrs) in 492 patients with skin basalioma and all cases of senile keratosis. No changes in peripheral blood count or any skin-resorption side-effects were recorded. Several patients suffered hyperemia, edema, itching or local pain.

• Authors: I A Studentsova, V I Romanov, R S Garaev
• Journal: Voprosy onkologii (Vopr Onkol) Vol. 45 Issue 4 Pg. 448-9 ( 1999) ISSN: 0507-3758 [Print] Russia (Federation)
• Vernacular Title: Opyt primeneniia glitsifonovoĭ mazi pri rake i predrakovykh zabolevaniiakh kozhi.
• PMID: 10532110 (Publication Type: English Abstract, Journal Article)

Chemical References

• Antineoplastic Agents
• Glyceryl Ethers
• Ointments
• glyciphonic ointment

Topics

• Adult
• Aged
• Aged, 80 and over
• Antineoplastic Agents (administration & dosage, therapeutic use)
• Carcinoma, Basal Cell (drug therapy)
• Female
• Glyceryl Ethers (therapeutic use)
• Humans
• Keratosis (drug therapy)
• Male
• Middle Aged
• Ointments
• Precancerous Conditions (drug therapy)
• Skin Neoplasms (drug therapy)
• Treatment Outcome