HLA-DQ1 associated with reflex sympathetic dystrophy.

Abstract

Reflex sympathetic dystrophy (RSD) is a relatively common disabling disorder of unknown pathophysiology. From a cohort of 52 patients, carefully selected to fulfill the recently formulated diagnostic criteria for RSD, venous blood samples were taken for typing of class I and II major histocompatibility antigens. The frequency of HLA-DQ1 was found to be significantly increased compared with control frequencies. The association provides an indication for an organic basis of RSD.

• Authors: M A Kemler, A C van de Vusse, E M van den Berg-Loonen, G A Barendse, M van Kleef, W E Weber
• Journal: Neurology (Neurology) Vol. 53 Issue 6 Pg. 1350-1 (Oct 12 1999) ISSN: 0028-3878 [Print] United States
• PMID: 10522900 (Publication Type: Journal Article)

Chemical References

• HLA-DQ Antigens
• HLA-DQ1 antigen

Topics

• HLA-DQ Antigens (immunology)
• Humans
• Reflex Sympathetic Dystrophy (immunology)