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[The mechanisms of the anti-ulcer action of plant drug agents].

Abstract
The mechanisms of the gastroprotective effect of well-known drugs (plantaglucid, befungin, plantain juice), extractions of birch bark (Betula pendula Roth,) and burdock seeds (Arctium tomentosum Mill.) on various links of gastric ulcer pathogenesis were compared. Phytopreparations were found to have a variety of effects on gastric secretion in rats. Differences in their action on the smooth muscles of the stomach and intestine were detected.
AuthorsO A Os'kina, V G Pashinskiĭ, T A Kanakina, T N Povet'eva, N V Gribel'
JournalEksperimental'naia i klinicheskaia farmakologiia (Eksp Klin Farmakol) 1999 Jul-Aug Vol. 62 Issue 4 Pg. 37-9 ISSN: 0869-2092 [Print] Russia (Federation)
Vernacular TitleNekotorye mekhanizmy protivoiazvennogo deĭstviia rastitel'nykh lekarstvennykh sredstv.
PMID10513334 (Publication Type: Comparative Study, Journal Article)
Chemical References
  • Anti-Ulcer Agents
  • Plant Extracts
  • Aspirin
Topics
  • Animals
  • Anti-Ulcer Agents (pharmacology, therapeutic use)
  • Aspirin
  • Drug Evaluation, Preclinical
  • Gastric Mucosa (drug effects, metabolism)
  • Gastrointestinal Motility (drug effects)
  • Mice
  • Plant Extracts (pharmacology, therapeutic use)
  • Rats
  • Rats, Wistar
  • Statistics, Nonparametric
  • Stomach Ulcer (chemically induced, drug therapy, physiopathology)

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