Abstract | BACKGROUND: OBJECTIVE: Our purpose was to determine the efficacy of SADBE in the treatment of recalcitrant warts. METHODS: We treated 29 patients with SADBE for warts that were resistant to other therapies. The patient population had warts for a mean duration of 2.1 years. Patients were sensitized with 1% or 2% SADBE in acetone under occlusion, then treated with 0.5% to 5% SADBE applied to their warts every 2 to 4 weeks in the office. RESULTS: Clearing of all warts was seen in 20 of 29 patients (69%), improvement in 3 patients (10%), and no change in 6 patients (21%). For the cured patients, mean duration of treatment was 4.2 months (range, 1 to 12 months) and mean number of treatments was 5.7 (range, 2 to 15). Adverse effects included acute contact dermatitis with 6 patients experiencing blisters and one experiencing hypopigmentation. CONCLUSION:
SADBE treatment is worth considering in patients with recalcitrant warts, especially in those who tolerate painful procedures poorly.
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Authors | A N Lee, S B Mallory |
Journal | Journal of the American Academy of Dermatology
(J Am Acad Dermatol)
Vol. 41
Issue 4
Pg. 595-9
(Oct 1999)
ISSN: 0190-9622 [Print] United States |
PMID | 10495383
(Publication Type: Journal Article)
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Chemical References |
- Allergens
- Cyclobutanes
- squaric acid dibutyl ester
|
Topics |
- Adolescent
- Adult
- Allergens
(adverse effects, immunology, therapeutic use)
- Child
- Child, Preschool
- Cyclobutanes
(adverse effects, immunology, therapeutic use)
- Female
- Humans
- Immunotherapy
- Infant
- Male
- Recurrence
- Warts
(therapy)
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