Abstract |
Crustacean hyperglycemic hormones (CHHs) are neuropeptides involved in the regulation of hemolymph glucose. The primary source of CHHs has been identified as the neurosecretory neurons of the eyestalk X-organ and its associated neurohemal organ, the sinus gland. We have identified another source of CHH-like peptides in the nervous system. With the use of immunocytochemistry, cells in the second roots of the thoracic ganglia have been observed to stain positively for CHH-reactive material. We also identified a pair of cells in the subesophageal ganglion that contain large amounts of CHH-reactive material. Depolarization of these cells with elevated potassium mediates a calcium-dependent release of CHH-like material from the ganglion as quantified with an enzyme-linked immunosorbent assay (ELISA).
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Authors | E S Chang, S A Chang, B S Beltz, E A Kravitz |
Journal | The Journal of comparative neurology
(J Comp Neurol)
Vol. 414
Issue 1
Pg. 50-6
(Nov 08 1999)
ISSN: 0021-9967 [Print] United States |
PMID | 10494077
(Publication Type: Journal Article, Research Support, Non-U.S. Gov't, Research Support, U.S. Gov't, Non-P.H.S.)
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Copyright | Copyright 1999 Wiley-Liss, Inc. |
Chemical References |
- Invertebrate Hormones
- Neuropeptides
- Glucose
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Topics |
- Animals
- Esophagus
(innervation)
- Ganglia, Invertebrate
(cytology, metabolism)
- Glucose
(metabolism)
- Hemolymph
(metabolism)
- Hyperglycemia
(metabolism)
- Immunohistochemistry
- Invertebrate Hormones
(metabolism)
- Nephropidae
(metabolism)
- Neuropeptides
(metabolism)
- Neurosecretory Systems
(physiology)
- Spinal Nerve Roots
(metabolism)
- Thorax
(innervation)
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