Lack of LH response to exogenous estradiol in heifers with ACTH-induced ovarian follicular cysts.

Abstract

The aim of the present study was to examine the LH response to exogenous estradiol in 4 heifers with ACTH-induced ovarian follicular cysts. During the control experiment, administration of estradiol 24 hr after PGF2alpha in luteal phase heifers resulted in a LH response in all 4 heifers. The LH response was obtained between 16-20 hr after estradiol administration. The peak LH concentration (Mean +/- SEM; 5.1 +/- 0.8 ng/ml) during the control study was significantly different (P<0.05) from the concentration after cyst formation. None of the 4 heifers responded to estradiol after ovarian cyst formation. This result suggests that heifers with ACTH-induced ovarian follicular cysts may have a defective hypothalamio-pituitary response to exogenous estradiol similar to cows with spontaneous ovarian cysts.

• Authors: A Y Ribadu, K Nakada, Y Tanaka, M Moriyoshi, W C Zhang, T Nakao
• Journal: The Journal of veterinary medical science (J Vet Med Sci) Vol. 61 Issue 8 Pg. 979-81 (Aug 1999) ISSN: 0916-7250 [Print] Japan
• PMID: 10487246 (Publication Type: Journal Article, Research Support, Non-U.S. Gov't)

Chemical References

• Estradiol
• Adrenocorticotropic Hormone
• Luteinizing Hormone

Topics

• Adrenocorticotropic Hormone
• Animals
• Cattle
• Cattle Diseases (blood)
• Estradiol (pharmacology)
• Female
• Luteinizing Hormone (blood)
• Ovarian Cysts (blood, chemically induced, veterinary)