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Laxifloranone, a new phloroglucinol derivative from Marila laxiflora.

Abstract
A new polyisoprenylated phloroglucinol derivative has been isolated from the twigs of Marila laxiflora and characterized on the basis of 1D and 2D NMR spectra. Laxifloranone (1) shows moderate inhibition of the cytopathic effects of in vitro HIV infection.
AuthorsH R Bokesch, A Groweiss, T C McKee, M R Boyd
JournalJournal of natural products (J Nat Prod) Vol. 62 Issue 8 Pg. 1197-9 (Aug 1999) ISSN: 0163-3864 [Print] United States
PMID10479340 (Publication Type: Journal Article, Research Support, U.S. Gov't, P.H.S.)
Chemical References
  • Anti-HIV Agents
  • laxifloranone
  • Phloroglucinol
Topics
  • Anti-HIV Agents (chemistry, isolation & purification, pharmacology)
  • Cell Line
  • Cytopathogenic Effect, Viral (drug effects)
  • HIV Infections (drug therapy)
  • Humans
  • Magnetic Resonance Spectroscopy
  • Phloroglucinol (analogs & derivatives, chemistry, isolation & purification, pharmacology)
  • Plants, Medicinal (chemistry)
  • Spectrometry, Mass, Fast Atom Bombardment

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