Clinical efficacy of two dentin desensitizing agents.

To compare the clinical effect over 3 months of two commercially available desensitizing agents on the level of discomfort of patients with complaints of dentin sensitivity.
An oxalate-containing pre-polymerized resin suspension (Pain-Free), a 0.7% fluoride solution (DentinBloc), and a distilled water placebo were compared in a clinical setting. Ten volunteer patients exhibiting three or more teeth that were sensitive to touch and to a stream of forced air were enrolled in the study (52 teeth total). Each patient's level of sensitivity to tactile stimuli and to a forced air stream was recorded using a visual analog scale (VAS). The tactile stimulus was a metal probe rubbed across the exposed dentin with a constant pressure of 40 grams. A 1-second blast of air from a dental unit air syringe was used to generate the air stream. The desensitizing agents were applied according to manufacturers' guidelines. Sensitivity measurements were recorded at baseline, immediately after treatment, at 1 week, 1 month, and at 3 months. VAS pain scores were analyzed using a repeated measures ANOVA (alpha = 0.05).
The pre-polymerized resin suspension (Pain-Free), the fluoride-containing solution (DentinBloc), and the placebo all decreased dentin sensitivity. No significant difference was found among the desensitizing agents at any time period (P > 0.05).
AuthorsM F Morris, R D Davis, B W Richardson
JournalAmerican journal of dentistry (Am J Dent) Vol. 12 Issue 2 Pg. 72-6 (Apr 1999) ISSN: 0894-8275 [Print] UNITED STATES
PMID10477986 (Publication Type: Clinical Trial, Comparative Study, Journal Article, Randomized Controlled Trial)
Chemical References
  • Dental Materials
  • DentinBloc
  • Organic Chemicals
  • Oxalates
  • Pain-Free
  • Adult
  • Analysis of Variance
  • Dental Materials (therapeutic use)
  • Dentin Sensitivity (prevention & control)
  • Female
  • Humans
  • Male
  • Organic Chemicals
  • Oxalates (therapeutic use)
  • Pain Measurement

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