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Successful treatment of refractory supraventricular tachycardia by repeat intravascular injection of amiodarone in a fetus with hydrops.

Abstract
We report the case of a fetus with supraventricular tachycardia complicated by congestive heart failure and ascites. After failure of initial transplacental treatment, the injection of amiodarone into the umbilical vein combined with evacuation of ascites achieved conversion to sinus rhythm and restored cardiac function thus allowing pregnancy to go to term. This report suggests that direct fetal therapy by umbilical vein puncture and evacuation of effusions constitutes an effective treatment for supraventricular tachycardias with massive fetal hydrops which do not respond to transplacental treatment.
AuthorsR Mangione, F Guyon, A Vergnaud, M Jimenez, R Saura, J Horovitz
JournalEuropean journal of obstetrics, gynecology, and reproductive biology (Eur J Obstet Gynecol Reprod Biol) Vol. 86 Issue 1 Pg. 105-7 (Sep 1999) ISSN: 0301-2115 [Print] Ireland
PMID10471151 (Publication Type: Case Reports, Journal Article)
Chemical References
  • Anti-Arrhythmia Agents
  • Digoxin
  • Amiodarone
Topics
  • Adult
  • Amiodarone (administration & dosage, therapeutic use)
  • Anti-Arrhythmia Agents (administration & dosage, therapeutic use)
  • Digoxin (administration & dosage, therapeutic use)
  • Female
  • Fetal Diseases (drug therapy)
  • Heart Rate, Fetal
  • Humans
  • Hydrops Fetalis (complications)
  • Injections, Intravenous
  • Pregnancy
  • Tachycardia, Supraventricular (complications, drug therapy)
  • Umbilical Veins

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