Atrioventricular nodal re-entrant tachycardia associated with stimulant treatment.

Abstract

A 13-year-old African-American female taking sertraline for obsessive compulsive disorder was diagnosed with her first episode of atrioventricular (AV) nodal re-entrant tachycardia five days after beginning Mixed Salts of a Single-Entity Amphetamine Product (Adderall) for treatment of attention-deficit hyperactivity disorder (ADHD). She received successful cardioversion with 6 mg of intravenous adenosine, but developed a second episode of possible AV nodal re-entrant tachycardia twelve days after Adderall was reinitiated at half the previous dose. The patient had clinically similar cardiac episodes five and six months after treatment was changed to slow-release methylphenidate. Stimulant medication may evoke onset of AV nodal tachyarrhythmias in patients who have the potential to develop them, possibly in combination with a selective serotonergic reuptake inhibitor (SSRI).

• Authors: B L Gracious
• Journal: Journal of child and adolescent psychopharmacology (J Child Adolesc Psychopharmacol) Vol. 9 Issue 2 Pg. 125-8 ( 1999) ISSN: 1044-5463 [Print] United States
• PMID: 10461823 (Publication Type: Case Reports, Journal Article)

Chemical References

• Adderall
• Amphetamines
• Central Nervous System Stimulants
• Methylphenidate

Topics

• Adolescent
• Amphetamines (adverse effects)
• Catheter Ablation
• Central Nervous System Stimulants (adverse effects)
• Drug Interactions
• Female
• Humans
• Methylphenidate (adverse effects)
• Tachycardia, Atrioventricular Nodal Reentry (chemically induced, surgery)