Forensic toxicological implication of acute fatal poisoning cases due to benfuracarb ingestion.

Abstract

We describe here three cases involving acute fatalities due to benfuracarb ingestion and the forensic toxicological implications. Benfuracarb, a carbamate insecticide and its main metabolite carbofuran, were detected using thin layer chromatography (TLC) and gas chromatography/mass spectrophotometry (GC/MS) after extraction with ethyl acetate and then quantified using gas chromatography (GC) equipped with NPD. The blood levels of benfuracarb and carbofuran were in the range of 0.30-2.32 microg/ml and 1.45-1.47 microg/ml, respectively. Benfuracarb was not detected in urine, but carbofuran was detected in the range of 0.53-2.66 microg/ml.

• Authors: S K Lee, K Ameno, J Y Yang, S W In, K U Kim, T J Kwon, Y C Yoo, T Kubota, S Ameno, I Ijiri
• Journal: International journal of legal medicine (Int J Legal Med) Vol. 112 Issue 4 Pg. 268-70 ( 1999) ISSN: 0937-9827 [Print] Germany
• PMID: 10433038 (Publication Type: Case Reports, Journal Article)

Chemical References

• Benzofurans
• Insecticides
• beta-Alanine
• benfuracarb
• Carbofuran

Topics

• Adult
• Benzofurans (analysis, poisoning)
• Carbofuran (analysis)
• Chromatography, Gas
• Chromatography, Thin Layer
• Female
• Gas Chromatography-Mass Spectrometry
• Humans
• Insecticides (analysis, poisoning)
• Male
• Poisoning (diagnosis)
• Suicide (legislation & jurisprudence)
• beta-Alanine (analogs & derivatives, analysis, poisoning)