[Prevention and treatment of postoperative pyoinflammatory complications and cefuroxime].

Abstract

Antibacterial activity and efficacy of cefuroxime (ketocef, Pliva, Zagreb) in the treatment and prophylaxis of surgical infections in a general hospital and particularly in the unit of vessel and aorta surgery, the unit of lung surgery and the unit of microsurgery were estimated. The study included 57 patients (43 males and 14 females) at the age of 21 to 70 years. Cefuroxime was administered intravenously in a dose of 1.5 g followed by its intramuscular administration in a dose of 750 mg with an interval of 8 hours. The results showed that cefuroxime was effective in the treatment (80 per cent) and prophylaxis (93.6 per cent) of the pyo-inflammatory complications and was active against the majority of the surgical infection pathogens.

• Authors: N S Bogomolova, T D Oreshkina, L V Bol'shakov
• Journal: Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic] (Antibiot Khimioter) Vol. 44 Issue 6 Pg. 27-32 ( 1999) ISSN: 0235-2990 [Print] Russia (Federation)
• Vernacular Title: Profilaktika i lechenie posleoperatsionnykh gnoĭno-vospalitel'nykh oslozhneniĭ s ispol'zovaniem tsefuroksima.
• PMID: 10422575 (Publication Type: Clinical Trial, Journal Article)

Chemical References

• Cephalosporins
• Cefuroxime

Topics

• Adult
• Aged
• Cefuroxime (therapeutic use)
• Cephalosporins (therapeutic use)
• Enterobacter (drug effects)
• Escherichia coli (drug effects)
• Female
• Humans
• Injections, Intramuscular
• Injections, Intravenous
• Male
• Microbial Sensitivity Tests
• Middle Aged
• Postoperative Complications (drug therapy, prevention & control)
• Staphylococcus (drug effects)