[Distribution of transplantation HLA antigens in children and adolescents with meningitis of various etiology].

Abstract

An interaction between HLA antigens and predisposition to meningitis of specific and nonspecific etiology was studied in children and adolescents from an Azerbaijan population. The distribution of HLA antigens was found to be heterogeneous in the patients with meningitis of various etiology. Tuberculous meningitis was characterized by a significant rise in the detection rate of HLA-DR3 antigen, by a considerable frequency of B14 and DR2 antigens; patients with purulent meningitis much more significantly showed HLA-B12 antigen; in terms of locus A, there was an increase in the detection rates of HLA-A19 antigen in serous meningitis.

• Authors: N A Feĭzullaeva
• Journal: Problemy tuberkuleza (Probl Tuberk) Issue 2 Pg. 43-4 ( 1999) ISSN: 0032-9533 [Print] Russia (Federation)
• Vernacular Title: Raspredelenie transplantatsionnykh antigenov sistemy HLA u deteĭ i podrostkov, boleiushchikh meningitami razlichnoĭ étiologii.
• PMID: 10420751 (Publication Type: Comparative Study, English Abstract, Journal Article)

Chemical References

• HLA Antigens
• HLA-A Antigens
• HLA-A19 antigen
• HLA-B Antigens
• HLA-B12 antigen
• HLA-B14 Antigen
• HLA-DR2 Antigen
• HLA-DR3 Antigen

Topics

• Adolescent
• Azerbaijan
• Child
• Genetic Predisposition to Disease
• HLA Antigens (analysis)
• HLA-A Antigens (analysis)
• HLA-B Antigens (analysis)
• HLA-B14 Antigen
• HLA-DR2 Antigen (analysis)
• HLA-DR3 Antigen (analysis)
• Humans
• Meningitis (etiology, genetics, immunology)
• Middle Aged
• Models, Theoretical
• Risk Factors
• Tuberculosis, Meningeal (etiology, genetics, immunology)