[A cryptococcal granuloma of the midbrain].

Abstract

The paper describes the most infrequent case of cryptococcal granuloma of the midbrain in a HIV-negative female patient aged 41 years. The patient with midbrain lesion without signs of meningitis was found to have a bulky midbrain opercular formation that was regarded as a nodal glioma. The diagnosis of cryptococcal granuloma was established after removal of the formation (via occipito-transtentorial access with dissection of the lamina tecti) and pathomorphological examination. Microbiological studies verified the diagnosis. Despite the initiation of specific treatment with amphotericin B, the patient died on day 12 following surgery for cryptococcal meningoencephalitis.

• Authors: A N Konovalov, D I Pitskhelauri, A G Korshunov, N V Arutiunov, V F Imshenetskaia, E A Khukhlaeva
• Journal: Zhurnal voprosy neirokhirurgii imeni N. N. Burdenko (Zh Vopr Neirokhir Im N N Burdenko) 1999 Apr-Jun Issue 2 Pg. 33-6 ISSN: 0042-8817 [Print] Russia (Federation)
• Vernacular Title: Kriptokokkovaia granulema srednego mozga.
• PMID: 10420545 (Publication Type: Case Reports, Journal Article, Review)

Topics

• Adult
• Brain Diseases (diagnosis, microbiology, pathology, surgery)
• Cryptococcosis (diagnosis, microbiology, pathology, surgery)
• Cryptococcus neoformans (isolation & purification)
• Fatal Outcome
• Female
• Granuloma (diagnosis, microbiology, pathology, surgery)
• HIV Seronegativity
• Humans
• Magnetic Resonance Imaging
• Mesencephalon (microbiology, pathology, surgery)