[The morphofunctional changes in the internal organs in the modelling of poisonings by psilocybine-containing mushrooms].

Abstract

Histological analysis of the viscera in experimental poisoning with psilocybin-containing mushrooms showed nonspecific changes in all examined organs, presenting as expressed hemocirculatory disorders and intracellular dystrophy. Quantitative histochemical analysis showed appreciable shifts in the activities of enzymes involved in the cytoplasmic and mitochondrial redox processes and of specific enzymes involved in nerve tissue metabolism. This may reflect some features in the direct effects of narcotic alkaloids contained in psilocybin-producing mushrooms.

• Authors: R V Babakhanian, G V Ivanova, T A Kostyrko, A E Safraĭ, O D Iagmurov
• Journal: Sudebno-meditsinskaia ekspertiza (Sud Med Ekspert) 1999 May-Jun Vol. 42 Issue 3 Pg. 6-9 ISSN: 0039-4521 [Print] Russia (Federation)
• Vernacular Title: Morfofunktsional'nye izmeneniia vnutrennikh organov pri modelirovanii otravleniĭ psilotsibinsoderzhashchimi gribami.
• PMID: 10396957 (Publication Type: Journal Article)

Chemical References

• Hallucinogens
• Psilocybin

Topics

• Aggression (drug effects)
• Analysis of Variance
• Animals
• Disease Models, Animal
• Hallucinogens (poisoning)
• Histocytochemistry
• Male
• Poisoning (metabolism, physiopathology)
• Psilocybin (poisoning)
• Rats
• Statistics, Nonparametric
• Viscera (metabolism, physiopathology)