Abstract | AIMS: METHODS: In a double masked random design, 24 patients with severe vernal keratoconjunctivitis were placed at random on nedocromil 2% eye drops in one eye and fluorometholone 0.1% in the fellow eye. At the end of the 2 week treatment period, the patient crossed over the eye drops (if asymptomatic in one eye), or continued with nedocromil sodium in both eyes (if asymptomatic in both eyes). All patients were examined weekly and ocular surface temperature recorded for a period of 6 weeks. RESULTS: Improvement in the watering, discharge, conjunctival hyperaemia, papillary hypertrophy, and Trantas' dots was noted in both groups, but overall fluorometholone was significantly more effective than nedocromil. Eyes treated with fluorometholone showed a significant decrease in ocular surface temperature compared with nedocromil treated eyes (p = 0.03). CONCLUSIONS:
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Authors | K F Tabbara, S A al-Kharashi |
Journal | The British journal of ophthalmology
(Br J Ophthalmol)
Vol. 83
Issue 2
Pg. 180-4
(Feb 1999)
ISSN: 0007-1161 [Print] England |
PMID | 10396195
(Publication Type: Clinical Trial, Comparative Study, Journal Article, Randomized Controlled Trial, Research Support, Non-U.S. Gov't)
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Chemical References |
- Anti-Inflammatory Agents
- Anti-Inflammatory Agents, Non-Steroidal
- Nedocromil
- Fluorometholone
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Topics |
- Adolescent
- Adult
- Anti-Inflammatory Agents
(therapeutic use)
- Anti-Inflammatory Agents, Non-Steroidal
(therapeutic use)
- Body Temperature
- Child
- Child, Preschool
- Double-Blind Method
- Female
- Fluorometholone
(therapeutic use)
- Humans
- Keratoconjunctivitis
(drug therapy)
- Male
- Nedocromil
(therapeutic use)
- Treatment Outcome
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