Study on the transmission threshold value of bancroftian filariasis.

Abstract

OBJECTIVE:

To elucidate the transmission dynamic and epidemic trend of bancroftian filariasis occurred under the condition with no control measure taken 5 years after elimination of filariasis.

METHODS:

A 10-year longitudinal observation (from 1984 to 1994) was made in Huayuan Village in Shengli Township of Tancheng County, which used to be a high bancroftian filariasis-endemic area in southern part of Shandong Province.

RESULTS:

The microfilarial rate decreased from 0.56% before the study to 0.12% after the study and 8 out of the 9 previous microfilaria-positive cases became negative gradually. During the study period, 6 new microfilaremia cases were detected, 5 of which became negative naturally within 3 to 4 years. Eighty-eight point eight nine per cent of the detected patients with microfilaremia converted into IgG4-negative after 10 years. The natural infective rate of vectors decreased year by year and became zero by the tenth year of the study, the annual transmission potency decreased also from 3.47 to zero by the tenth year.

CONCLUSIONS:

It showed that under the local natural environment the biting rate representing the vector density which was obtained by capture method was from 24.1 to 52.5 person/night among the residents who did not use mosquito nets, and 13.5 to 21 person/night among the residents who used mosquito nets. The microfilarial rate of 0.56% in population with the average microfilarial density of 6.6 to 20.7 capita/60 microliters ear blood of residual microfilaria-positive patients might be considered as the terminal threshold of transmission.

• Authors: P Wang, F Wang, Y Sun, J Wang, J Kou, Y Huang, X Kang, G Wan, Y Liang, Q Wang
• Journal: Chinese medical journal (Chin Med J (Engl)) Vol. 111 Issue 3 Pg. 261-4 (Mar 1998) ISSN: 0366-6999 [Print] China
• PMID: 10374430 (Publication Type: Journal Article, Research Support, Non-U.S. Gov't)

Topics

• Animals
• Culex (parasitology)
• Female
• Filariasis (epidemiology, prevention & control, transmission)
• Humans
• Insect Vectors (parasitology)
• Longitudinal Studies
• Male
• Microfilariae
• Wuchereria bancrofti