Sclerosing peritonitis and systemic lupus erythematosus: a report of two cases.

Abstract

OBJECTIVE:

To heighten the awareness of a possible association of sclerosing peritonitis in patients with systemic lupus erythematosus (SLE).

METHODS AND RESULTS:

Over the course of 17 years (from January 1981 to December 1997), 371 patients were treated with continuous ambulatory peritoneal dialysis (CAPD) at Rush-Presbyterian-St Lukes Medical Center. The patients were followed on CAPD for an average of 25 +/- 21 (SD) months with a median of 19 months (range 0.2-115 months). During this time only 2 (0.5%) patients were diagnosed with sclerosing peritonitis, and both had SLE with ongoing evidence of active disease while on CAPD. With a total of 26 SLE patients being treated with CAPD during the observation period, the prevalence of sclerosing peritonitis can be said to be as high as 8% in this patient population.

CONCLUSION:

These cases suggest that autoimmune diseases, such as SLE, that are well known to cause immune-mediated serositis may represent an additional factor predisposing to the development of sclerosing peritonitis in patients treated with CAPD.

• Authors: U O Odama, D J Shih, S M Korbet
• Journal: Peritoneal dialysis international : journal of the International Society for Peritoneal Dialysis (Perit Dial Int) 1999 Mar-Apr Vol. 19 Issue 2 Pg. 160-4 ISSN: 0896-8608 [Print] United States
• PMID: 10357188 (Publication Type: Case Reports, Journal Article)

Topics

• Adult
• Female
• Humans
• Kidney Failure, Chronic (therapy)
• Lupus Erythematosus, Systemic (complications)
• Lupus Nephritis (therapy)
• Peritoneal Dialysis, Continuous Ambulatory
• Peritoneum (pathology)
• Peritonitis (epidemiology, etiology, pathology)
• Prevalence
• Retrospective Studies
• Risk Factors
• Sclerosis