[Recurrent osteitis and Coxiella burnetii: the relation to chronic recurrent multifocal osteomyelitis].

Abstract

UNLABELLED:

Chronic recurrent multifocal osteomyelitis (CRMO) is a disorder of suspected--but unproved-infectious etiology.

OBSERVATION:

A girl presented with a typical CRMO involving successively the left fibula, radius, humerus and the right carpus. A Coxiella burnetii infection was indicated during the first attack. Two recurrences occurred in spite of suitable antibiotic treatment and with negative infectious investigation. Two months after stopping antibiotic treatment, a new recurrence associated with antibodies increase and positive bone culture occurred.

CONCLUSION:

Coxiella burnetii can initiate a CRMO. The mechanism involved is probably a delayed hypersensitivity. CRMO would therefore be the first type of reactive osteitis.

• Authors: A Poujol, S Toesca, J N Di Marco, Y Rimet, H Tissot Dupont, L Macé, N Sudan, M Panuel, Y Turcat, F Kelberine, Y Brusquet
• Journal: Archives de pediatrie : organe officiel de la Societe francaise de pediatrie (Arch Pediatr) Vol. 5 Issue 3 Pg. 291-4 (Mar 1998) ISSN: 0929-693X [Print] France
• Vernacular Title: Ostéites récidivantes et Coxiella burnetti: relation avec l'ostéomyélite chronique récurrente multifocale.
• PMID: 10327998 (Publication Type: Case Reports, English Abstract, Journal Article)

Chemical References

• Anti-Bacterial Agents

Topics

• Anti-Bacterial Agents (therapeutic use)
• Carpal Bones (microbiology)
• Child, Preschool
• Chronic Disease
• Coxiella burnetii (classification)
• Female
• Fibula (microbiology)
• Humans
• Humerus (microbiology)
• Osteitis (microbiology)
• Osteomyelitis (microbiology)
• Q Fever
• Radius (microbiology)
• Recurrence