Methenamine hippurate ('Hiprex') in the treatment of chronic urinary tract infections: a trial in a geriatric hospital.

Abstract

Fifty-two patients, all of whom were more than 66 years-old and who were hospitalized for periods in excess of two years were treated for chronic urinary tract infection. All patients received a course of antibiotic treatment for seven to ten days and were then put onto treatment with methenamine hippurate 1 g twice daily for six months. Of the original fifty-two patients, twelve did not complete the six month course. During the six month period with "Hiprex' there were far fewer re-infections than in the previous six months during which time they had received intermittent antibiotic therapy and other long-term treatment. There were no adverse reactions and bacterial resistance did not occur.

• Authors: S Parvio
• Journal: The Journal of international medical research (J Int Med Res) Vol. 4 Issue 2 Pg. 111-4 ( 1976) ISSN: 0300-0605 [Print] England
• PMID: 1026539 (Publication Type: Journal Article)

Chemical References

• Methenamine

Topics

• Aged
• Chronic Disease
• Drug Evaluation
• Female
• Humans
• Methenamine (adverse effects, analogs & derivatives, therapeutic use)
• Recurrence
• Urinary Tract Infections (drug therapy)