Transfer factor for the lung, airway obstruction and hyperinflation in chronic bronchitis and emphysema.

Abstract

The interrelationships of breath holding lung transfer factor (TCO) and transfer coefficient (KCO) with ventilatory obstruction (FEV1.0) and FEV1.0/VC) and hyperinflation (RV and RV/TLC) were studied in 37 patients with chronic nonspecific lung disease with a FEV1.0 of 1.5 litre or less classified as "bronchitic", "emphysematous" or "intermediate" according to Nash, Briscoe and Cournand (1965). No relationships could be found between TCO and airway obstruction or hyperinflation. KCO tended to decrease as RV increased (r=-0.26) and was weakly related to the FEV1.0/VC ratio in "intermediate" (r=0.34) and "emphysema" (r=0.29) patients but these relationships were nonsignificant.

• Authors: D B Teculescu, M A Manicatide, C L Racoveanu
• Journal: Medecine interne (Med Interne) 1976 Apr-Jun Vol. 14 Issue 2 Pg. 125-31 ISSN: 0377-1202 [Print] Romania
• PMID: 1024251 (Publication Type: Journal Article)

Chemical References

• Carbon Dioxide

Topics

• Adult
• Bronchitis (physiopathology)
• Carbon Dioxide
• Chronic Disease
• Diagnosis, Differential
• Forced Expiratory Volume
• Humans
• Lung Volume Measurements
• Male
• Middle Aged
• Pulmonary Alveoli (physiopathology)
• Pulmonary Diffusing Capacity
• Pulmonary Emphysema (physiopathology)
• Residual Volume
• Respiration
• Respiratory Function Tests
• Total Lung Capacity
• Vital Capacity