[Effect of Bunaftine on the ventricular tachycardia due to aconitine in the dog].

Abstract

Suppression of aconitine-induced ventricular tachycardia in the dog with various doses of Bunaftine was attempted. Stable re-establishment of the sinus rhythm was achieved in only 3/15 cases, whereas in 3 tachicardia was unchanged, and in 9 fibrillation appeared, due, it is thought, to the effect of the drug on myocardial conductivity, since fibrillation was the most frequent outcome when high doses were used.

• Authors: A Alella, C Bertin, D Gattullo, G Losano, G Vacca
• Journal: Archivio per le scienze mediche (Arch Sci Med (Torino)) 1976 Oct-Dec Vol. 133 Issue 4 Pg. 363-70 ISSN: 0004-0312 [Print] Italy
• Vernacular Title: Azione della bunaftine sulla tachicardia ventricolare da aconitina nel cane
• PMID: 1023842 (Publication Type: English Abstract, Journal Article)

Chemical References

• Anti-Arrhythmia Agents
• Butylamines
• Naphthalenes
• Aconitine

Topics

• Aconitine
• Animals
• Anti-Arrhythmia Agents (pharmacology, therapeutic use)
• Butylamines (pharmacology, therapeutic use)
• Disease Models, Animal
• Dogs
• Myocardial Contraction (drug effects)
• Naphthalenes (pharmacology, therapeutic use)
• Tachycardia (chemically induced, drug therapy)