| Abstract | The case of a 54-year-old woman with metastatic follicular thyroid cancer and undetectable serum thyroglobulin is presented. Many years after the patient had a subtotal thyroidectomy for a large goiter that had no clear evidence of malignancy, metastatic bone disease developed. When the bone metastases were detected and during the follow-up period, serum thyroglobulin values remained undetectable, but radioiodine uptake in the metastases was abundant. This case indicates that the combination of 1-131 scintigraphy and serum thyroglobulin values is superior to the measurement of serum thyroglobulin alone in detecting well-differentiated, metastatic thyroid cancer. |
| Authors | I J Mertens, J M De Klerk, P M Zelissen, J H Thijssen, D M Sie-Go, S H Han, P P Van Rijk
(Affiliation: Department of Nuclear Medicine, University Hospital Utrecht, The Netherlands.)
|
| Journal | Clinical nuclear medicine
(Clin Nucl Med)
Vol. 24
Issue 5
Pg. 346-9
(May 1999)
ISSN: 0363-9762 UNITED STATES |
| PMID | 10232475
(Publication Type: Case Reports, Journal Article)
|
| Chemical References |
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| Topics |
- Adenocarcinoma, Follicular
(diagnosis, radionuclide imaging, secondary)
- Bone Neoplasms
(diagnosis, radionuclide imaging, secondary)
- Female
- Humans
- Middle Aged
- Thyroglobulin
(blood)
- Thyroid Neoplasms
(pathology)
|
