[Embolia cutis medicamentosa (Nicolau syndrome) after intra-articular injection].

Abstract

Embolia cutis medicamentosa (Nicolau Syndrome) is a very rare complication of intramuscular injections which presents with extensive necrosis of the injected skin area. Intra-arteria and/or para-arterial injections after prior perforation of certain vessels are discussed as possible pathogenetic mechanisms. We describe the occurrence of embolia cutis medicamentosa after intra-articular injections into the knee.

• Authors: S Beissert, D Presser, A Rütter, D Metze, T A Luger, T Schwarz
• Journal: Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete (Hautarzt) Vol. 50 Issue 3 Pg. 214-6 (Mar 1999) ISSN: 0017-8470 [Print] Germany
• Vernacular Title: Embolia cutis medicamentosa (Nicolau-Syndrom) nach intraartikulärer Injektion.
• PMID: 10231693 (Publication Type: Case Reports, Journal Article)

Chemical References

• Anti-Inflammatory Agents
• Sclerosing Solutions
• Polidocanol
• Polyethylene Glycols
• prednisolone acetate
• Prednisolone

Topics

• Anti-Inflammatory Agents (administration & dosage, adverse effects)
• Embolism (chemically induced, pathology)
• Humans
• Injections, Intra-Articular (adverse effects)
• Knee Joint (blood supply, drug effects)
• Male
• Middle Aged
• Necrosis
• Polidocanol
• Polyethylene Glycols (administration & dosage, adverse effects)
• Prednisolone (administration & dosage, adverse effects, analogs & derivatives)
• Sclerosing Solutions (administration & dosage, adverse effects)
• Skin (blood supply, pathology)
• Syndrome