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Immunoprotective effect of IM-133.

Abstract
We studied the immunoprotective effect of IM-133, a poly-herbal formulation, against E. coli-induced intra-abdominal sepsis. Treatment with IM-133 afforded protection against the septic shock induced mortality. The in vivo treatment has enhanced nitric oxide production and phagocytic ability against C. albicans by peritoneal macrophages in Balb/c mice. The protective effect of IM-133 appears to be by virtue of its immunomodulatory activity and finds application in the clearance of intra-cellular pathogens.
AuthorsS K Mitra, M Gupta, T Suryanarayana, D N Sarma
JournalInternational journal of immunopharmacology (Int J Immunopharmacol) Vol. 21 Issue 2 Pg. 115-20 (Feb 1999) ISSN: 0192-0561 [Print] England
PMID10230874 (Publication Type: Journal Article)
Chemical References
  • Adjuvants, Immunologic
  • Nitric Oxide
Topics
  • Adjuvants, Immunologic (pharmacology)
  • Animals
  • Female
  • Male
  • Medicine, Ayurvedic
  • Mice
  • Mice, Inbred BALB C
  • Nitric Oxide (biosynthesis)
  • Phagocytosis (drug effects)
  • Phytotherapy

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