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[Problems produced by the use of antitubercular agents in a reference service for HIV/AIDS in Abidjan (Côte d'Ivoire)].

Abstract
This study reports on the experience using antituberculosis drugs in a HIV/AIDS reference service in Abidjan during a 64 month period. Prevalence of tuberculosis is 1.9% out of a total of 23,957 patients. The annual incidence rate increased slowly from 0.9% in 1990 to 3.5% in 1995. Seropositivity to HIV is 90.8%. Predominant locations of tuberculosis are pulmonary (60.3%), extrapulmonary (19.7%) and multifocal or disseminated (20%). The average period of diagnosis (9.9 days) and average duration of antituberculosis treatment in hospital (11.8 days) are similar whatever the serological status and the location of the infection may be. However, the mortality rate is more important in HIV positive patients (39.7%) than in HIV negative (17.6%) p = 0.01. The decision to treat is taken by infectiologists only in 88% of the cases, by pneumologists only in 2.5%, and both by infectiologists and pneumologists in 9.5%. Side-effects due to antituberculosis drugs were noticed in 19 patients leading to an interruption of the treatment in 10 cases. The authors recommend that health personnel be trained for the management of tuberculosis.
AuthorsA Kakou, S Eholie, B Yao, M Coulibaly, E Ehui, E Bissagnéné, E Aoussi, A Kadio
JournalBulletin de la Societe de pathologie exotique (1990) (Bull Soc Pathol Exot) Vol. 92 Issue 1 Pg. 42-5 (Feb 1999) ISSN: 0037-9085 [Print] France
Vernacular TitleProblèmes engendrés par l'utilisation des antituberculeux dans un service de référence pour VIH/SIDA à Abidjan (Côte d'Ivoire).
PMID10214521 (Publication Type: English Abstract, Journal Article)
Chemical References
  • Antitubercular Agents
Topics
  • Acquired Immunodeficiency Syndrome (complications)
  • Adolescent
  • Adult
  • Aged
  • Aged, 80 and over
  • Antitubercular Agents (adverse effects)
  • Cote d'Ivoire (epidemiology)
  • Female
  • HIV Seropositivity
  • Humans
  • Male
  • Middle Aged
  • Tuberculosis (complications, drug therapy, epidemiology)

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