Ability of a rapid serology test to detect seroconversion to herpes simplex virus type 2 glycoprotein G soon after infection.

Abstract

Sera (n = 188) from 29 patients with first-episode genital herpes simplex virus type 2 (HSV-2) infections were tested by POCkit-HSV-2 and Western blot (WB) to determine the speed of seroconversion. The median time to detection of HSV-2 antibody was 13 days (range, 3 to 102 days) by the POCkit-HSV-2 test versus 13 days (range, 2 to 58 days) for WB.

• Authors: R L Ashley, M Eagleton, N Pfeiffer
• Journal: Journal of clinical microbiology (J Clin Microbiol) Vol. 37 Issue 5 Pg. 1632-3 (May 1999) ISSN: 0095-1137 [Print] United States
• PMID: 10203544 (Publication Type: Journal Article, Research Support, Non-U.S. Gov't, Research Support, U.S. Gov't, P.H.S.)

Chemical References

• Antibodies, Viral
• Immunoglobulin G
• Immunoglobulin M
• Viral Envelope Proteins

Topics

• Antibodies, Viral (blood)
• Blotting, Western
• Herpesvirus 2, Human (immunology)
• Humans
• Immunoglobulin G (blood)
• Immunoglobulin M (blood)
• Time Factors
• Viral Envelope Proteins (immunology)