Abstract | OBJECTIVE: METHODS: This was a randomized, clinical trial with parallel design. 94 children <18 years of age seen in the ED of a tertiary care pediatric hospital with a facial laceration suitable for tissue adhesive closure underwent laceration closure using either butylcyanoacrylate or octylcyanoacrylate. The primary outcome was the cosmetic result at three months rated from photographs by a plastic surgeon on a visual analog scale (VAS). Secondary outcomes included the time to perform the procedure, the perceived difficulty of the procedure, the pain perceived by the patient, and a wound evaluation score at ten to 14 days and three months. RESULTS: Ninety-four patients were randomized with 47 in each group. The two groups were similar for baseline demographic and clinical characteristics. There was no difference in the three-month cosmesis VAS (median, 70.0 mm for n-butyl-2-cyanoacrylate vs 67.5 mm for octylcyanocrylate, p = 0.84). There was no difference between the groups for time to complete the procedure (p = 0.88), parent/patient-perceived pain of the procedure (p = 0.37), or physician-perceived difficulty of the procedure (p = 0.33). Similarly, there was no difference between the groups for the percentage of early (p = 0.58) or late (p = 0.71) optimal wound evaluation scores. CONCLUSIONS:
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Authors | M H Osmond, J V Quinn, T Sutcliffe, M Jarmuske, T P Klassen |
Journal | Academic emergency medicine : official journal of the Society for Academic Emergency Medicine
(Acad Emerg Med)
Vol. 6
Issue 3
Pg. 171-7
(Mar 1999)
ISSN: 1069-6563 [Print] United States |
PMID | 10192666
(Publication Type: Clinical Trial, Comparative Study, Journal Article, Randomized Controlled Trial, Research Support, Non-U.S. Gov't)
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Chemical References |
- Cyanoacrylates
- Tissue Adhesives
- octylcyanoacrylate
- Enbucrilate
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Topics |
- Child
- Child, Preschool
- Cyanoacrylates
(therapeutic use)
- Enbucrilate
(therapeutic use)
- Facial Injuries
(therapy)
- Female
- Humans
- Male
- Pain Measurement
- Prospective Studies
- Tissue Adhesives
(therapeutic use)
- Treatment Outcome
- Wound Healing
(drug effects)
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