Abstract |
The absolute configuration of an enantiomer of the title compound, (+/-)-1. fumaric acid salt, was determined by X-ray crystallographic analysis of (+)-1 [ salt of (+)- tartaric acid [(+)-2]]. This salt for X-ray crystallographic analysis was prepared by a simple method. The analysis of (+)-1 [ salt of (+)-2] showed that this enantiomer has the 5-S and 1-R absolute configuration. The final R and Rw values were 0.0614 and 0.0713, respectively.
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Authors | S Yoshida, M Yamamoto, Y Aoki, H Nohira |
Journal | Chirality
(Chirality)
Vol. 11
Issue 3
Pg. 256-60
( 1999)
ISSN: 0899-0042 [Print] United States |
PMID | 10079504
(Publication Type: Journal Article)
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Chemical References |
- Morpholines
- Muscle Relaxants, Central
- NC 1800
- Oxazoles
- Oxazolidinones
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Topics |
- Animals
- Crystallography, X-Ray
- In Vitro Techniques
- Molecular Conformation
- Morpholines
(chemistry, pharmacokinetics, therapeutic use)
- Muscle Relaxants, Central
(chemistry, pharmacokinetics, therapeutic use)
- Muscle, Skeletal
(metabolism)
- Oxazoles
(chemistry, pharmacokinetics, therapeutic use)
- Oxazolidinones
- Rats
- Stereoisomerism
- Urinary Bladder
(drug effects)
- Urination Disorders
(drug therapy)
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