Methimazole embryopathy: delineation of the phenotype.

Abstract	We report on a further case of congenital anomalies in a child exposed to methimazole during the first trimester of pregnancy (from first to seventh gestational week), and define a specific malformation pattern related to prenatal methimazole exposure and consisting of choanal and esophageal atresia, scalp defects, minor facial anomalies and psychomotor delay.
Authors	M Clementi, E Di Gianantonio, E Pelo, I Mammi, R T Basile, R Tenconi
Journal	American journal of medical genetics (Am J Med Genet) Vol. 83 Issue 1 Pg. 43-6 (Mar 05 1999) ISSN: 0148-7299 [Print] United States
PMID	10076883 (Publication Type: Case Reports, Journal Article, Review)
Chemical References	Antithyroid Agents Teratogens Methimazole
Topics	Abnormalities, Drug-Induced (genetics) Adult Antithyroid Agents (toxicity) Child, Preschool Choanal Atresia (chemically induced) Esophageal Atresia (chemically induced) Female Graves Disease (drug therapy) Humans Male Maternal-Fetal Exchange Methimazole (toxicity) Phenotype Pregnancy Pregnancy Trimester, First Teratogens

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