| Abstract | The value of whole body PET-FDG in the evaluation of metastases has been demonstrated in a wide variety of tumors. In this report, we present the case of a patient with antecedent of papillary thyroid carcinoma, who was operated twelve years ago, and submitted to an ablative dose of residual thyroid tissue through 131I, being the levels of thyroglobulin normals. After twelve years of evolution, the patient refers bag pain and respiratory trouble, appearing in the CT image suspicious of metastases in right pulmonary base. The levels of thyroglobulin were shown increased, being the 131I scan negative. A whole body PET-FDG study was performed in order to exclude metastases of his malignant process, showed multiple high FDG uptake focus in brain, cerebellum, neck, chest, lymphatic nodes and bone, suggestive of dedifferentiated disease These findings were confirmed subsequently in the clinic evolution. Therefore, whole-body PET-FDG is a complementary diagnostic technique for study patients with CDT (Thyroid Differentiated Carcinoma) with 131I scan negative and rising thyroglobulin levels. |
| Authors | F Ortega, A Maldonado, P Marañes, R Montz, M J Pérez-Castejón, M Melgarejo, J A Ruiz, J L Carreras
(Affiliation: Centro PET Complutense, Madrid 28040, España.)
|
| Journal | Revista española de medicina nuclear
(Rev Esp Med Nucl)
Vol. 18
Issue 1
Pg. 50-4
( 1999)
ISSN: 0212-6982 SPAIN |
| Vernacular Title | La PET-FDG en el cáncer de tiroides ante niveles altos de tiroglobulina y rastro 131-I negativo. A Propósito de un caso. |
| PMID | 10074219
(Publication Type: Case Reports, English Abstract, Journal Article)
|
| Chemical References |
- Fluorine Radioisotopes
- Iodine Radioisotopes
- Thallium Radioisotopes
- Tumor Markers, Biological
- Deoxyglucose
- Thyroglobulin
|
| Topics |
- Aged
- Bone Neoplasms
(radionuclide imaging, secondary)
- Brain Neoplasms
(radionuclide imaging, secondary)
- Carcinoma, Papillary
(radionuclide imaging, radiotherapy, secondary, surgery)
- Cell Differentiation
- Deoxyglucose
(analogs & derivatives, diagnostic use)
- False Negative Reactions
- Fluorine Radioisotopes
(diagnostic use)
- Humans
- Iodine Radioisotopes
(diagnostic use, therapeutic use)
- Lymphatic Metastasis
(radionuclide imaging)
- Male
- Neoplasm Metastasis
(radionuclide imaging)
- Neoplasm Recurrence, Local
(radionuclide imaging)
- Thallium Radioisotopes
(diagnostic use)
- Thoracic Neoplasms
(radionuclide imaging, secondary)
- Thyroglobulin
(blood)
- Thyroid Neoplasms
(pathology, radionuclide imaging, radiotherapy, surgery)
- Thyroidectomy
- Tomography, Emission-Computed
- Tumor Markers, Biological
(urine)
|
