Fluconazole therapy in Candida albicans spondylodiscitis.

Abstract

A case of Candida albicans spondylodiscitis in a 20-year-old female liver transplant recipient is reported. The patient was successfully treated with sequential therapy with liposomal amphotericin B and fluconazole. A review of the literature showed 10 cases of Candida albicans spondylodiscitis successfully treated either with fluconazole alone or a sequential therapy with amphotericin B and fluconazole. If long-term amphotericin B therapy is not feasible, a prolonged course of fluconazole in a daily dose of 200-400 mg may be considered as an alternative.

• Authors: P Rössel, H C Schønheyder, H Nielsen
• Journal: Scandinavian journal of infectious diseases (Scand J Infect Dis) Vol. 30 Issue 5 Pg. 527-30 ( 1998) ISSN: 0036-5548 [Print] England
• PMID: 10066061 (Publication Type: Case Reports, Journal Article)

Chemical References

• Antifungal Agents
• Amphotericin B
• Fluconazole

Topics

• Adult
• Amphotericin B (therapeutic use)
• Antifungal Agents (therapeutic use)
• Candida albicans (isolation & purification)
• Candidiasis (diagnosis, drug therapy)
• Discitis (drug therapy, microbiology)
• Drug Therapy, Combination
• Female
• Fluconazole (therapeutic use)
• Humans
• Liver Transplantation