[A case of multiple liver metastases showing good response by administration of carmofur alone in an aged patient with colorectal cancer].

Abstract

An 85-year-old woman had an elevated serum tumor marker CEA, and CT examination revealed multiple liver metastases. The patient was treated with oral administration of 200 mg/day of carmofur (HCFU) alone in our hospital. As a result, more than 60% of the focuses of liver metastasis disappeared, and the level of CEA decreased. The present case seems to show that liver metastases were significantly decreased by chemotherapy with oral administration of HCFU by itself. Thus, the case suggests that HCFU is useful for the treatment of liver metastases from colorectal cancer.

• Authors: T Matsuda, K Mabuchi, H Kitaoka, N Hirata, U Kitaoka
• Journal: Gan to kagaku ryoho. Cancer & chemotherapy (Gan To Kagaku Ryoho) Vol. 26 Issue 3 Pg. 357-9 (Feb 1999) ISSN: 0385-0684 [Print] Japan
• PMID: 10065100 (Publication Type: Case Reports, Journal Article)

Chemical References

• Antineoplastic Agents
• carmofur
• Fluorouracil

Topics

• Adenocarcinoma (drug therapy, secondary)
• Administration, Oral
• Aged
• Aged, 80 and over
• Antineoplastic Agents (administration & dosage)
• Colonic Neoplasms (drug therapy, pathology)
• Drug Administration Schedule
• Female
• Fluorouracil (administration & dosage, analogs & derivatives)
• Humans
• Liver Neoplasms (drug therapy, secondary)